Müller-cell-derived leukaemia inhibitory factor arrests rod photoreceptor differentiation at a postmitotic pre-rod stage of development
… and when it becomes a rhodopsin + rod. We show that FCS arrests rod development in
these cultures at a postmitotic, rhodopsin − , pre-rod stage. We present evidence that FCS acts …
these cultures at a postmitotic, rhodopsin − , pre-rod stage. We present evidence that FCS acts …
[图书][B] Studies in the differentiation and survival of mammalian rod photoreceptors
C Neophytou - 1997 - search.proquest.com
… calf serum (PCS) in these cultures arrests rod differentiation at a postmitotic, pre-rod stage of
… cells, which is mediated by leukaemia inhibitory factor (LIT). The … Müller cell-derived LIF …
… cells, which is mediated by leukaemia inhibitory factor (LIT). The … Müller cell-derived LIF …
Leukemia Inhibitory Factor Prevents Photoreceptor Cell Death in rd-/- Mice by Blocking Functional Differentiation: LIF alters gene expression in photoreceptors
JD Ash - New Insights Into Retinal Degenerative Diseases, 2001 - Springer
… LIF can inhibit functional maturation of rod photoreceptors. LIF … This age represents the most
active period of cell death in rd-Imice (… In addition, the photoreceptors failed to develop outer …
active period of cell death in rd-Imice (… In addition, the photoreceptors failed to develop outer …
[HTML][HTML] Leukemia inhibitory factor blocks expression of Crx and Nrl transcription factors to inhibit photoreceptor differentiation
DR Graham, PA Overbeek… - … ophthalmology & visual …, 2005 - jov.arvojournals.org
… In the initial phase, dividing progenitors become postmitotic … In development, cells in the
photoreceptor lineage turn on … step for the expression of both rod and cone photoreceptor genes. …
photoreceptor lineage turn on … step for the expression of both rod and cone photoreceptor genes. …
Soluble factors and the development of rod photoreceptors
… The stages of rod photoreceptor differentiation are shown along with … Muller-cell-derived
leukaemia inhibitory factor arrests rod photoreceptor differentiation at a postmitotic pre-rod stage …
leukaemia inhibitory factor arrests rod photoreceptor differentiation at a postmitotic pre-rod stage …
[HTML][HTML] Progression from extrinsic to intrinsic signaling in cell fate specification: a view from the nervous system
T Edlund, TM Jessell - Cell, 1999 - cell.com
… One hallmark of such inhibitory factors is that they do not … of postmitotic neurons or glial cells
occurs over a protracted … and promote the differentiation of glial cells at the expense of rod …
occurs over a protracted … and promote the differentiation of glial cells at the expense of rod …
[HTML][HTML] STAT3-mediated signaling in the determination of rod photoreceptor cell fate in mouse retina
SSM Zhang, J Wei, H Qin, L Zhang… - … & visual science, 2004 - iovs.arvojournals.org
… factor (CNTF) and leukemia inhibitory factor (LIF) negatively regulate the development of
rod photoreceptors … of rod photoreceptor differentiation, we used a specific inhibitor of MAPK …
rod photoreceptors … of rod photoreceptor differentiation, we used a specific inhibitor of MAPK …
[HTML][HTML] Cross-talk between neurons and glia: highlights on soluble factors
FCA Gomes, T Spohr, R Martinez… - Brazilian Journal of …, 2001 - SciELO Brasil
The development of the nervous system is guided by a balanced action between intrinsic
factors represented by the genetic program and epigenetic factors characterized by cell-cell …
factors represented by the genetic program and epigenetic factors characterized by cell-cell …
[HTML][HTML] Involvement of Pleiotrophin in CNTF-mediated differentiation of the late retinal progenitor cells
J Roger, V Brajeul, S Thomasseau, A Hienola… - Developmental …, 2006 - Elsevier
… in progenitor cells then in postmitotic precursors of the INL … rod differentiation and promotes
bipolar cell production, similar to effects of exogenous CNTF and leukemia inhibitory factor (…
bipolar cell production, similar to effects of exogenous CNTF and leukemia inhibitory factor (…
Effects of ciliary neurotrophic factor on differentiation of late retinal progenitor cells
… ), IL‐11, leukemia inhibitory factor, and oncostatin M. The effects … early, postmitotic
photoreceptors into rod photoreceptors that … Once we have developed in vitro differentiation …
photoreceptors into rod photoreceptors that … Once we have developed in vitro differentiation …